Urubuga-rwihariye Kwishyira hamwe Kwinjiza neza Intego ya Genes ahantu hashyushye

Kwishyira hamwe kurubuga rwihariye muri selile ya CHO ninzira ikoreshwa mugutangiza gene yinyungu ahantu hasobanuwe neza muri genome ya selile ya hamster ovary (CHO).Iyi nzira ikubiyemo gukoresha urubuga rwihariye rwa recombinase enzyme kugirango ugere ku rutonde rwihariye muri genome selile CHO hanyuma ugahuza gene yinyungu muburyo bukurikirana.Ubu buryo butuma hashobora kugenzurwa neza kwinjiza gen muri selile ya CHO kandi birashobora gufasha kwirinda kwishyira hamwe, bishobora kugira ingaruka zidasanzwe kuri selile.Ibyiza byingenzi byubu buryo nuko bitanga igenzura ryinshi nukuri kubikorwa byo kwishyira hamwe, kimwe nurwego runini rwo gutuza kwa gene mugihe.Byongeye kandi, ubu buryo burashobora gukoreshwa mugutangiza genes nyinshi ahantu hatandukanye muri selire, bigatuma iba igikoresho gikomeye cyo gukoresha gene.